Common NMR Solvents

SolventMol. Wt.D420 (g/mL)mp*bp*δH (mult)**δC (mult)**
Acetic acid-d4 64.078 1.12 17 118 11.53 (1)
2.03 (5)
178.4 (br)
20.0 (7)
Acetone-d6 64.117 0.87 -94 57 2.04 (5) 206.0 (13)
29.8 (7)
Acetonitrile-d3 44.071 0.84 -45 82 1.93 (5) 118.2 (br)
1.3 (7)
Benzene-d6 84.152 0.95 5 80 7.15 (br) 128.0 (3)
Carbon tetrachloride 153.81 1.59 -23 77 96.0 (1)
Chloroform-d 120.384 1.50 -64 62 7.24 (1) 77.0 (3)
Cyclohexane-d12 96.236 0.89 6 81 1.38 (br) 26.4 (5)
Deuterium oxide 20.028 1.11 3.8 101.4 4.63***
4.67(Na3PO4)
 
Diglyme-d14 148.263 0.95 -68 162 3.49 (br)
3.40 (br)
3.22 (br)
70.7 (5)
70.0 (5)
57.7 (7)
Dimethyl formamide-d7 80.138 1.04 -61 153 8.01 (br)
2.91 (5)
2.74 (5)
162.7 (3)
35.2 (7)
30.1 (7)
Dimethyl sulfoxide-d6 84.170 1.18 18 189 2.49 (5) 39.5 (7)
p-Dioxane-d8 96.156 1.13 12 101 3.53 (m) 66.5 (5)
Methyl alcohol-d4 36.067 0.89 -98 65 4.78 (1)
3.30 (5)
49.0 (7)
Methylene chloride-d2 86.945 1.35 -95 40 5.32 (3) 53.8 (5)
Nitromethane-d3 64.059 1.20 -29 101 4.33 (5) 62.8 (7)
Pyridine-d5 84.133 1.05 -42 116 8.71 (br)
7.55 (br)
7.19 (br)
149.9 (3)
135.5 (3)
123.5 (3)
Tetrahydrofuran-d8 80.157 0.99 -109 66 3.58 (br)
1.73 (br)
67.4 (5)
25.3 (br)
Toluene-d8 100.191 0.94 -95 111 7.09 (m)
7.00 (br)
6.98 (m)
2.09 (m)
137.5 (1)
128.9 (3)
128.0 (3)
125.2 (3)
20.4 (7)
Trifluoroacetic acid-d 115.030 1.50 -15 72 11.50 (1) 164.2 (4)
116.6 (4)

* Melting and boiling points (°C) are those of the corresponding light compound (except for D2O).
** δH = chemical shift of residual protons; δC = 13C chemical shift (both relative to TMS). Mult = multiplicity of peak (m = broad peak with fine structure; br = broad peak without fine structure).
*** Since TMS is insoluble in water, reference is (CH3)3Si(CH2)3SO3Na (DSS).

Reference: Merck, Sharpe & Dohme compilation.